INNOVATIVE SYNTHESIS OF DERIVATIVES OF 4-ETHYLBENZOIC ACID AND 4-ETHYLCYCLOHEXANECARBOXYLIC ACID
Keywords:
4-Ethylbenzoic, 4-ethylcyclohexanecarboxylic acid, pharmaceutical industry, catalytic agentsAbstract
This research aims to prepare new derivatives of 4-ethylbenzoic acid and 4-ethylcyclohexanecarboxylic acid using a variety of organic reactions including amine esterification and hydrogenation. First, 4-ethylbenzoic acid was prepared by oxidation of 4-ethyltoluene with potassium permanganate in basic medium, and then this compound was hydrogenated to obtain 4-ethylcyclohexanecarboxylic acid. Then, ester and amine derivatives were prepared by substitution reactions using catalysts to modify the chemical properties of the resulting compounds. The chemical structures of the prepared compounds were confirmed by elemental analysis (CHN) and using infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy techniques, which showed that the analytical data were consistent with the expected structures. The results in previous studies indicate that derivatives containing amino groups may possess strong antibacterial properties. This research is a step towards exploring the pharmaceutical and chemical applications of these acid derivatives, as the prepared compounds can be used in developing drugs or chemicals with improved properties. It also opens the way for further studies related to the biological and chemical activity of these compounds in the future.
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