THE INHIBITORY EFFECT OF RUE PEGANUM HARMALA EXTRACTS ON PATHOGENIC FUNGI
Keywords:
fungi, pomegranate, inhibition, extract, concentrationAbstract
Medicinal plants have been used for therapeutic purposes since ancient times. Peganum Harmala, in particular, has been recognized for its potential anti-fungal properties due to the presence of alkaloids and flavonoids. This study aimed to investigate the effect of Peganum Harmala extracts on the growth of pathogenic fungi. Three types of extracts were prepared: aqueous, alcoholic, and acidic, using powdered seeds, stems, and leaves of the plant. The effect of the extracts on fungal growth was tested using the Disk diffusion method.
The results showed a variable effect against the studied fungal species, Aspergillus and Candida. The sulfuric acid extract was the most effective in inhibiting fungal growth, exhibiting the highest inhibition zone diameter (48 mm). The aqueous extract showed no effect on fungal growth, while the alcoholic extract exhibited a variable effect, inhibiting some species at certain concentrations but showing no effect on others.
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