THE ROLE OF HEMATOLOGICAL PARAMETERS IN IDENTIFYING MODERATE FROM SEVERE COVID-19 CASES
Keywords:
COVID-19, Neutrophil-to-Lymphocyte Ratio, hematological parameters, severityAbstract
Background: As severe cases of Coronavirus disease 2019 (COVID-19) may deteriorate rapidly and develop acute respiratory distress syndrome so finding simple useful indicators to predict the severity of the disease is very helpful in its management.Methods :We collected some personal and hematology data from 108 patients with COVID-19 infection for retrospective analysis. The cases were divided into two groups; severe and moderate .Results: The differences of white blood cells and platelets between the two groups were non-significant (P >0.05). On the other hand, the differences between the two groups regarding lymphocyte count and percentage, neutrophils count and percentage, hemoglobin concentration, red blood cells , neutrophil-to-lymphocyte ratio (NLR) were significant, (P<0.05). It was obvious that neutrophils percentage was the most accurate studied parameter in predicting the severity of COVID-19 infection (The area under the curve (AUC), cut-off, sensitivity and specificity were 0.732, 80.15%, 78%, 70.1% respectively.), followed by NLR ( The AUC, cut-off, sensitivity and specificity were 0.725, 5.75, 75.6%, 62.7% respectively).Conclusion: several hematological parameters can help in early detection of the severity of the COVID-19 infection. The widest AUC was of neutrophil percentage followed by that of NLR.
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