دراسة الفاعلية التثبيطية لمستخلصات الزيوت الطيـــارة مـــن أوراق نباتي إكليـــل الجبـــل (ROSMARINUS OFFICINALIS) المليسة (LIPPIA CITRIODORA) علي بعض أنواع المبيضات جنس CANDIDA
DOI:
https://doi.org/10.59743/jbs.v35i1.122Keywords:
Essential oils, Rosmarinus officinalis and Lippia citriodoraAbstract
Plants and herbs are most important resources of many medicinal substances, action toward improve many illness cases affecting human beings and animals. Region of Jabal al Gharbi "Western Mountain", Libya is rich of those medicinal herbs. This study was conducted to investigate the effectiveness of leaf essential oils of Rosmarinus officinalis and Lippia citriodora using different concentrations on isolated types of Candida (Candida. albicans, Candida. glabrata and Candida. paraseloius) compared to antifungal effects of common antimycotic compounds (Nystatin and Miconazole). applied on according to the outcome of antimycotic sensitivity test, Nystatin shows a high inhibition zone (8, 9 and 15 mm) on isolated Candida (C. albicans, C. glabrata and C. paraseloius) respectively, which revealed a various resistance to (Miconazole), while 100% concentration of leaf essential oil of R. officinalis show an inhibition zone (8.8, 4.8 and 7.4 mm) on isolated Candida (C. albicans, C. glabrata and C. paraseloius) respectively. As for 70% concentration of leaf essential oil of R. officinalis reveals a highly inhibition zone (15 mm) on C. paraseloius with Significant difference of (p<0.05) compared to other concentrations. while 20% concentration of leaf essential oil of R. officinalis Has less inhibition zone (6, 3.2 and 5 mm) on isolated Candida (C. albicans, C. glabrata and C. paraseloius) respectively.
Inhibitiory effects of leaf essential oils of L. citriodora was lower than what seen in R. officinalis. 100 % concentration of leaf essential oil of L. citriodora revealed highest inhibition zone (9.8 and 5.2) on isolated Candida (C. albicans and C. glabrata) respectively, while no effect was seen on isolated C. paraseloius. On the other hand, 50% concentration had an inhibition effect on isolated C. albicans, and C. paraseloius, with inhibition zone of 6.8 mm and 5 mm, respectively, otherwise there were no inhibition effect detected on C. glabrata. 20% concentration leaf essential oils of L. citriodora did not reveal any inhibitiory effect on mentioned isolated Candida.
Current study concluded that the leaves essential oils of R. officinalis and L. citriodora have inhibitory activities against isolated Candida (C. albicans, C. glabrata and C. paraseloius). However, the leaves essential oils of R. officinalis were more effective compared to the leaves essential oils of L. citriodora.
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