Assessment of Hematological and Biochemical Indicators in Relation to Thyroid Function in Hemodialysis Patients in Al Khums City, Libya
DOI:
https://doi.org/10.59743/jmset.v11i2.192Keywords:
Biochemical parameters, Blood parameters, Chronic kidney disease, Thyroid hormones, DialysisAbstract
Chronic Kidney Disease (CKD) is a global health problem. Secondary hyperparathyroidism is common in dialysis patients and contributes to bone disorders and vascular calcification. This study, conducted at Al-Khums Kidney Hospital, Libya, from July to December 2024, included 150 participants: 100 dialysis patients (50 males and 50 females) and 50 healthy individuals (25 males and 25 females). Hematological parameters such as hemoglobin (HGB) and red blood cell count (RBC) and biochemical markers such as urea, creatinine, TSH, T3, and T4 were measured using standard laboratory methods. Patients showed significantly elevated creatinine (9.55±2.55 mg/dL), urea (148.88±34.61 mg/dL), and TSH (3.56±0.62 μIU/mL), and decreased T3 (0.96±0.19 ng/mL), T4 (6.56±0.62 μg/dL), and HGB (10.92±1.87 g/dL) compared to the control group. Pearson correlation analysis revealed statistically significant negative correlations between urea and T3, creatinine and T3, and between hemoglobin and both urea and creatinine. Conversely, we found statistically significant positive correlations between urea and creatinine, red blood cells and T3, and urea and TSH. These results underscored the importance of regularly monitoring thyroid function and blood parameters in dialysis patients to minimize potential complications
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