Risk Factors and Maternal Outcome Following Preterm Premature Rupture of Membrane in Second Trimester of Gestation

Abstract

PPROM (preterm premature rupture of membranes) occurs in about 1% of pregnancies, and makes up one-third of all premature deliveries. Spontaneous miscarriage often follows PPROM that occurs during the second trimester of pregnancy; thus, many countries allow elective termination of ongoing pregnancies after PPROM. Infections during pregnancy (including asymptomatic bacteriuria) must be treated due to the potential for serious maternal and fetal consequences associated with PPROM during the pregnancy. This study examines maternal outcomes and risk factors associated with preterm premature rupture of membranes at 2nd trimester; it is retrospective, descriptive and cohort based. A total of 1053 women who delivered their baby at Zliten Medical Centre, Zliten, Libya, between January 2022 and March 2025 comprised the population of this investigation. Women with PPROM had a history of constant amniotic fluid loss prior to admission and typically had a gestational age of greater than 35weeks 19 weeks(44.91 percent). There is a wide variety of height (less than 155 to greater than 170 cm) and weight (within both tall and small ranges). Socio economic determinants are made up of variables including occupation, education and religion. Maternal health outcomes are determined by preterm premature rupture of membranes, vaginal bleeding during pregnancy, number of antenatal care visits, types of delivery and infant birth weight (in grams)..